REJURAN Bio-regenerator

Rejuran treatment comprises of wild salmon polynucleotides which help to boost collagen, reduce sebum production, and improve the appearance of pores.


Rejuran Bio-regenerator

Rejuran is a concentrated injectable polynucleotide that is extracted from wild salmon sperm DNA. Polynucleotides (PDRN) are long chains of amino acids found naturally in the skin, playing an important role in skin remodelling at cellular level. By prompting fibroblasts into action, Rejuran encourages your body to produce its own collagen and elastin, the building blocks of youthful, supple skin.

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Wild Salmon Polynucleotides

Reduces wrinkles


Collagen and elastin loss are major contributors to wrinkles. By boosting their production, Rejuran helps smooth the skin, promoting a firmer appearance.

enhances skin hydration

Enhances Hydration

By stimulating fibroblast activity, Rejuran indirectly boosts HA production, leading to increased skin hydration from within, leaving your skin feeling plump and dewy.

Improves skin texture

Improves Skin Texture

By prompting fibroblasts, Rejuran encourages the production of new skin cells. This helps to shed damaged cells, revealing a brighter, more even tone.

Reduces scars

Reduces Scars

This treatment can help remodel scar tissue, filling in pitted scars and smoothing out raised ones, which will minimise their appearance.

choosing your

Rejuran Skin Treatment

rejuran skin treatment for eyes

Rejuran i

Rejuran I, through fibroblast stimulation, indirectly boosts hyaluronic acid (HA) production. HA acts as a humectant, attracting and retaining moisture within the skin, leading to a plumper, smoother under-eye area. Rejuran I's thinner consistency allows for precise injections in the delicate under-eye region compared to thicker Rejuran formulations used in other areas. This minimizes the risk of swelling or complications.

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Rejuran S

Rejuran S injections trigger fibroblasts, the collagen-producing cells, to work harder. This enhanced activity leads to increased collagen production. The new collagen helps fill in pitted scars, while smoothing out raised ones. The PDRN may play a role in tissue repair, contributing to the breakdown of existing scar tissue and encouraging the growth of healthier skin cells, leading to a smoother, more even texture.

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Rejuran Classic

Covering larger surface area than Rejuran i & Rejuran S, Rejuran Classic is administered through a series of fine injections into the target areas. It is typically administered to areas such as the face, neck, hands or décolletage, but it is not limited to these areas. The PDRN acts as a messenger, stimulating the natural regenerative processes within your skin cells, plumping up the skin, whilst restoring tightness and elasticity.

your journey

Rejuran Skin Treatment


Have a personalised consultation with our skincare nurse, understanding the requirements, and offered treatments at Sisä Skincare.


Rejuran is performed after a topical anaesthetic is applied to the skin and left for 30-50 minutes. The skin will be cleansed and the treatment will begin.


Your treatment will be provided by our Founder, and Registered Nurse, Chelsea. Depending on the area being treated, this can take anywhere from 15 - 30 minutes.

Post-Treatment Care

Prioritise gentle cleansing, and avoid direct sun exposure and rigorous activities for a short period to allow your skin the tranquility it needs to rejuvenate.


Tips and Suggestions

We understand that personalisation is key to achieving optimal skincare results. During your consultation with our Registered Nurse, we will carefully assess your unique skin concerns and goals. We’ll discuss factors like skin type, desired level of correction, and treatment areas to determine the ideal Morpheus8 RF settings and treatment plan. This customized approach ensures you receive the most effective treatment for your specific needs, maximizing your journey towards healthier skin. 

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Before Your Treatment:

  • Consultation: During your skin consultation, our nurse will discuss your medical history, current at-home skincare routine, and desired results.We’ll also answer any questions you may have about the treatment process.
  • Preparation: We may recommend temporarily discontinuing certain medications or skincare products that can thin the blood or irritate the skin.
  • Sun Protection: Avoid excessive sun exposure for at least two weeks prior to your treatment to minimize the risk of hyperpigmentation.

After Your Treatment:

  • Mild Discomfort: You may experience some redness, swelling, and mild discomfort after your treatment. This is completely normal and typically subsides within a few days.
  • Moisturizing: It’s crucial to keep your skin well-hydrated following the treatment. We’ll recommend gentle, fragrance-free moisturizers to soothe and accelerate healing.
  • Sun Protection: Continued sun protection is essential post-treatment. Always wear sunscreen with SPF 30 or higher to safeguard your newly rejuvenated skin.
  • Makeup: Avoid applying makeup for at least 24 hours after your treatment to allow your skin time to heal.
  • Saunas and Strenuous Activity: Avoid strenuous exercise, hot showers, saunas, and swimming pools for at least 48 hours to prevent further irritation.
  • Hydration: Proper hydration is crucial both before and after your treatment. Aim to drink plenty of water throughout the day to support your skin’s healing process and maintain its elasticity.
  • Healthy Lifestyle: A balanced diet rich in antioxidants and essential nutrients helps nourish your skin from within and promotes optimal healing.
  • Supplement Power: Consider incorporating collagen-boosting supplements like Vitamin C or marine collagen peptides into your routine to further enhance your results.
  • Post-Treatment Skincare Routine: Stick to a gentle, fragrance-free skincare routine after your treatment. Harsh products can irritate your skin and hinder healing.
  • Exfoliation: After the initial healing period (typically around a week), gentle exfoliation can help remove dead skin cells and promote smoother texture. Consult your skincare professional for recommended exfoliation products and techniques.
  • Embrace Skincare Consistency: Consistency is key to maintaining your results. Following a regular skincare routine that includes cleansing, moisturizing, and SPF protection will help you achieve long-lasting youthful radiance.
  • Schedule Follow-Up Treatments: For optimal results, a series of three Morpheus8 RF Microneedling treatments spaced four weeks apart is often recommended. We can discuss a personalized treatment plan during your consultation. 

Frequently Asked Questions

Rejuran treatments can address wrinkles, fine lines, loss of elasticity, uneven skin tone, and texture. Some, like Rejuran S, specifically target scars.

After recieving the recommended treatment plan of three treatments, spaced four weeks apart, results from Rejuran typically last 6-18 months, depending on the specific treatment and individual factors. 

The number of treatments needed varies depending on your individual concerns and desired outcome. Typically, three sessions spaced four weeks apart are recommended for optimal results, with some improvement often visible after just one session.

Rejuran treatments are minimally invasive, so downtime is usually minimal. You may experience slight redness or swelling, which typically subsides within a few days.

Potential side effects are usually mild and temporary, such as redness, bruising, or mild swelling. More serious side effects are rare. All risks and side effects are discussed with our Registered Nurse and Doctors during the consultation process to determine suitability for treatment.

Yes, Sisä Skincare offers a wide range of skin and laser treatments. The healing process of some of our treatments can even be expedited when paired with Rejuran. This can be discussed during your initial skin consultation with our Registered Nurse to ensure suitability.